MOTS-C is a mitochondria-derived peptide consisting of 16 amino acids. Its name refers to a mitochondrial open reading frame within the 12S rRNA region.
MOTS-C has been investigated in cell-based and mouse studies of mitochondrial signaling and cellular metabolism. A 2015 study examined its relationship with the folate-purine pathway and AMPK, an enzyme involved in cellular energy sensing. These findings describe experimental models, not expected outcomes from a Limitless Biotech product.
Available material and documentation
The MOTS-C peptide for sale from Limitless Biotech is identified by the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg, molecular formula C101H152N28O22S2, and molecular weight 2,174.6 g/mol. Review the selected weight and grade alongside the applicable product specifications.
Premium Lyophilized material is manufactured in the United States and has a minimum purity specification of at least 99%. Its testing program includes independent purity and quantitative testing, plus sterility and endotoxin testing.
Standard Non-Lyophilized material has a minimum purity specification of at least 98.5%; the raw material is manufactured overseas, with Limitless Biotech handling vialing, internal quality control, and independent purity testing.
This product may contain trehalose as a lyoprotectant/solubility agent. Match storage instructions to the selected material and its current condition. Instructions for unopened lyophilized material do not establish the storage conditions or lifetime of material in solution.
The Limitless Biotech MOTS-C peptide is only available for in vitro research studies. It is not appropriate for human or animal use.
Available Certificates of Analysis (COAs) provide analytical results for the tested material. Match the compound, material grade, labeled amount, and batch to the report. Chromatographic purity does not establish the amount of MOTS-C in the sample; quantitative testing addresses that separate question where included.
Research context
A 2018 study in cultured cells investigated AMPK-dependent movement of MOTS-C into the nucleus during metabolic stress and associated changes in gene expression. This provides a defined context for cellular research rather than evidence of personal metabolic or longevity outcomes.
Explore Mitochondrial Research for related research materials, or browse our research peptides to compare individual compounds.
For broader handling considerations, review our peptide storage and handling guide alongside the material-specific instructions. View MOTS-C specifications and log in for professional pricing.
- Sequence:
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Molecular Formula:
- C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular Weight:
- 2174.6 g/mol
- CAS Number:
- 1627580-64-6
- PubChem CID:
- 255386757
- Synonyms:
- Mitochondrial open reading frame of the 12S rRNA-c, 12S rRF-encoded mitochondrial peptide
- Purity:
- ≥99% (HPLC)
- Solubility:
- Soluble in sterile water
- Storage Conditions:
- Store at ≤-18°C (lyophilized), 2-8°C after reconstitution (short term)
- Physical Appearance:
- White lyophilized powder
- Shelf Life:
- 36 months from date of manufacture when stored properly
- Quality Verification:
- Third-party tested by certified laboratory
- Manufacturing Standard:
- USA-made, pharmaceutical-grade, GMP compliant
- Intended Application:
- In vitro research applications only (RUO)
At Limitless Biotech, we provide comprehensive Certificates of Analysis (COAs) for all of our research-only peptides to ensure transparency, purity, and quality in every batch. Each COA includes detailed analytical data that allows researchers to verify identity, concentration, and integrity, supporting reliable and reproducible scientific work. Our commitment to rigorous testing helps researchers move forward with confidence in the materials they use.
MOTS-C 5mg #1268 Endotoxin COA
MOTS-C 5mg #1268 Sterility COA
MOTS-C 5mg #1264 Purity COAMOTS-C 5mg #1264 Sterility COAMOTS-C 5mg #1264 Endotoxin COA
MOTS-C 10mg #1260 Sterility COAMOTS-C 10mg #1260 Purity COAMOTS-C 10mg #1260 Endotoxin COA
